POLYMORPHIC VARIANTS OF XENOBIOTIC METABOLISM GENES AND BODY MASS INDEX IN SCHIZOPHRENIA PATIENTS RECEIVING ANTIPSYCHOTIC THERAPY

Polymorphic variants of xenobiotic metabolism genes and body mass index in schizophrenia patients receiving antipsychotic therapy

The use of atypical antipsychotic drugs has made metabolic disorders one of the most common side effect of pharmacotherapy for schizophrenic patients.The aim of this study was to assess the contribution of polymorphic variants of genes of the P450 cytochrome system to changes in body mass index in patients with schizophrenia.As a result of the stud

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Ethical issues in pragmatic randomized controlled trials: a review of the recent literature identifies gaps in ethical argumentation

Abstract Background Pragmatic randomized controlled trials (RCTs) are designed to evaluate the effectiveness of interventions in real-world clinical conditions.However, these studies raise ethical issues for researchers and regulators.Our objective is to identify a list of key ethical issues in pragmatic RCTs and highlight gaps in the ethics litera

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Survey of referrals and medical reports in optometric practices in Norway: midterm findings from a 3-year prospective Internet-based study

Per O Lundmark,1 Knut Luraas1,2 1Department of Optometry, Radiography and Lighting Design, Faculty of Health and Social Sciences, University College of Southeast Norway, Kongsberg, 2Rjukan Synssenter Optometri, Rjukan, Norway Purpose: The increasing demand for primary eye care due to an aging population implicates an enhanced role of optometrists i

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